{"id":15,"date":"2023-09-06T14:07:07","date_gmt":"2023-09-06T14:07:07","guid":{"rendered":"https:\/\/demosites.royal-elementor-addons.com\/solar-energy-v1\/?page_id=15"},"modified":"2025-03-05T15:17:23","modified_gmt":"2025-03-05T15:17:23","slug":"team","status":"publish","type":"page","link":"https:\/\/gicar.quimica.unlp.edu.ar\/?page_id=15","title":{"rendered":"Publicaciones"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"15\" class=\"elementor elementor-15\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-f92f5ea elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"f92f5ea\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-85f8c95 elementor-invisible\" data-id=\"85f8c95\" data-element_type=\"column\" data-settings=\"{&quot;animation&quot;:&quot;slideInLeft&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-908f70d elementor-widget-laptop__width-initial elementor-widget elementor-widget-heading\" data-id=\"908f70d\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.21.0 - 26-05-2024 *\/\n.elementor-heading-title{padding:0;margin:0;line-height:1}.elementor-widget-heading .elementor-heading-title[class*=elementor-size-]>a{color:inherit;font-size:inherit;line-height:inherit}.elementor-widget-heading .elementor-heading-title.elementor-size-small{font-size:15px}.elementor-widget-heading .elementor-heading-title.elementor-size-medium{font-size:19px}.elementor-widget-heading .elementor-heading-title.elementor-size-large{font-size:29px}.elementor-widget-heading .elementor-heading-title.elementor-size-xl{font-size:39px}.elementor-widget-heading .elementor-heading-title.elementor-size-xxl{font-size:59px}<\/style><h2 class=\"elementor-heading-title elementor-size-default\">Publicaciones<br><\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-5829cee elementor-hidden-tablet elementor-hidden-mobile elementor-invisible\" data-id=\"5829cee\" data-element_type=\"column\" data-settings=\"{&quot;animation&quot;:&quot;slideInRight&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-065cc0c elementor-widget elementor-widget-image\" data-id=\"065cc0c\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.21.0 - 26-05-2024 *\/\n.elementor-widget-image{text-align:center}.elementor-widget-image a{display:inline-block}.elementor-widget-image a img[src$=\".svg\"]{width:48px}.elementor-widget-image img{vertical-align:middle;display:inline-block}<\/style>\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"478\" height=\"360\" src=\"https:\/\/gicar.quimica.unlp.edu.ar\/wp-content\/uploads\/2024\/07\/PublicacionesFOto.png\" class=\"attachment-large size-large wp-image-2249\" alt=\"\" srcset=\"https:\/\/gicar.quimica.unlp.edu.ar\/wp-content\/uploads\/2024\/07\/PublicacionesFOto.png 478w, https:\/\/gicar.quimica.unlp.edu.ar\/wp-content\/uploads\/2024\/07\/PublicacionesFOto-300x226.png 300w\" sizes=\"(max-width: 478px) 100vw, 478px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t<div class=\"elementor-element elementor-element-2f2952a e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-parent\" data-id=\"2f2952a\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-261e1a7 elementor-widget elementor-widget-text-editor\" data-id=\"261e1a7\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.21.0 - 26-05-2024 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<p>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;\u00faltimos 15 a\u00f1os&#8230;<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ddf6875 e-con-full e-flex wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-parent\" data-id=\"ddf6875\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-25ed13f elementor-widget-laptop__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"25ed13f\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>-An Efficient Synthetic Methodology for the Preparation of Glycosyl \u03b2-Diketones. I. A. Barri, M. S. Le Pors and P. A. Colinas. European Journal of Organic Chemistry <strong>2025.<\/strong><\/p><p>DOI: <span style=\"color: #000000;\"><a style=\"color: #000000;\" href=\"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/10.1002\/ejoc.202401366\">10.1002\/ejoc.202401366<\/a><\/span><\/p><p>-Glucoimines incorporating classical and non-classical carbonic anhydrase pharmacophores: design, synthesis, conformational analysis, biological evaluation, and docking simulations. I. I. V\u00e1squez, L. E. Riafrecha, L. Mart\u00ednez Heredia, G. A. Echeverr\u00eda, O. E. Piro, M.J. Lavecchia, C.T. Supuran and P. A. Colinas. Journal of molecular structure <strong>2024<\/strong>, 1321,139798.<\/p><p>DOI: <span style=\"color: #000000;\"><a style=\"color: #000000;\" href=\"https:\/\/doi.org\/10.1016\/j.molstruc.2024.139778\">10.1016\/j.molstruc.2024.139778<\/a><\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u2013Spontaneous resolution of diastereomeric glycosyl isoxazolines: a combined theoretical and experimental study in solution and in the crystalline form. <\/span><span lang=\"ES\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: ES;\">I. A. Barri, L. E. Riafrecha, G. A. Echeverr\u00eda,\u00a0 O. E. Piro\u00a0 and P. A. Colinas. Journal of molecular structure <b>2024<\/b>. 1310,138252<\/span><\/p><p><span style=\"font-size: 12.0pt; line-height: 107%; font-family: 'Arial',sans-serif;\">DOI: <a href=\"http:\/\/dx.doi.org\/10.1016\/j.molstruc.2024.138252\" target=\"_blank\" rel=\"noopener\"><span style=\"color: windowtext;\">10.1016\/j.molstruc.2024.138252<\/span><\/a><\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u2013Glycosyl Isoxazoles for Targeting of Tumor Microenvironment and Cancer Cells: Highly Selective Inhibitors of Carbonic Anhydrases IX and XII Showing Cytotoxic Activity. <\/span><span lang=\"ES\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: ES;\">M.S. Le Pors, L. Santa Mar\u00eda de la Parra, L.E. Riafrecha, D. Vullo, I.E. Leon, C.T. Supuran and P.A. Colinas. <\/span><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">ChemistrySelect <b>2023<\/b>, 8(11). 10.1002\/slct.202300039.<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">DOI:<\/span><span style=\"font-size: 12.0pt; line-height: 107%; font-family: 'Arial',sans-serif;\"><a href=\"http:\/\/dx.doi.org\/10.1002\/slct.202300039\" target=\"_blank\" rel=\"noopener\"><span style=\"color: windowtext;\">10.1002\/slct.202300039<\/span><\/a><\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u2013Green Biphasic Synthesis, X\u2013Ray Diffraction Structure and Conformational Analysis of <i>O<\/i>\u2013Glycosylmethyl<br \/>Isoxazoles: Potential Substrates of GLUT-1 Glucose Transporter. <\/span><span lang=\"ES\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: ES;\">M.S. Le Pors, I.A. Barri, L. E.\u00a0 Riafrecha, G. A. Echeverr\u00eda, O. Piro and P. A. Colinas.<\/span><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u00a0ChemistrySelect\u00a0<b>2022<\/b>, 26, 2601\u20132608.<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">DOI<\/span><span style=\"font-size: 12.0pt; line-height: 107%; font-family: 'Arial',sans-serif;\">: <a href=\"http:\/\/dx.doi.org\/10.1002\/slct.202104379\" target=\"_blank\" rel=\"noopener\"><span style=\"color: windowtext;\">10.1002\/slct.202104379<\/span><\/a><\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u2013Vanillin enones as selective inhibitors of the cancer associated carbonic anhydrase isoforms IX and XII. The out of the active site pocket for the design of selective inhibitors? .<\/span><span lang=\"ES\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: ES;\">L. E.\u00a0 Riafrecha, M.S. LePors, M.J. Lavecchia, S. Bua, C. T: Supuran and P. A. Colinas. <\/span><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">Journal of enzyme inhibition and medicinal chemistry <b>2021<\/b>, 36 (1), 2118\u20132127.<\/span><\/p><p><span style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif;\">DOI:\u00a0<\/span><span style=\"font-size: 12.0pt; line-height: 107%; font-family: 'Arial',sans-serif;\"><a href=\"https:\/\/doi.org\/10.1080\/14756366.2021.1982933\" target=\"_blank\" rel=\"noopener\"><span style=\"color: windowtext;\">10.1080\/14756366.2021.1982933<\/span><\/a><\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u2013<i>C<\/i>\u2013cinnamoyl\u00a0\u00a0 glycosides:\u00a0 an\u00a0\u00a0 emerging\u00a0\u00a0 \u201ctail\u201d\u00a0 \u00a0for the development of selective carbonic anhydrase inhibitors. <\/span><span lang=\"ES\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: ES;\">H. Llant\u00e9n, L. E.\u00a0 Riafrecha and P. A. Colinas. Current Medicinal Chemistry <b>2019<\/b>, 26, 2601\u20132608.<\/span><\/p><p><span style=\"font-size: 12.0pt; line-height: 107%; font-family: 'Arial',sans-serif;\">DOI:\u00a0<a href=\"http:\/\/dx.doi.org\/10.2174\/0929867325666180713122907\"><span style=\"color: windowtext;\">10.2174\/0929867325666180713122907<\/span><\/a><\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u2013Improving the carbonic anhydrase inhibition profile of the sulfamoylphenyl pharmacophore by attachment of carbohydrate moieties. <\/span><span lang=\"ES\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: ES;\">L. E. Riafrecha, S. Bua, C. T. Supuran and P. A. Colinas. <\/span><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">Bioorganic Chemistry <b>2018<\/b>, 76, 61\u201366.<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">DOI:10.1016\/j.bioorg.2017.10.020<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u00a0<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u2013Synthesis of <i>C<\/i>-glycosylmethyl isoxazoles via aerobic oxidation of ketoximes catalyzed by TEMPO. <\/span><span lang=\"ES\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: ES;\">H. Llant\u00e9n, S.Barata\u2013Vallejo, A. Postigo and P. A. Colinas. <\/span><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">Tetrahedron Letters <b>2017<\/b>, 58, 1507\u20131511.<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\"><a title=\"Enlace persistente mediante identificador de objeto digital\" href=\"https:\/\/doi.org\/10.1016\/j.tetlet.2017.03.005\" target=\"_blank\" rel=\"noopener\"><span lang=\"ES-AR\" style=\"color: windowtext;\"><span style=\"border-bottom: transparent; transition: border-bottom-color 0.3s ease 0s;\">DOI: <\/span><span style=\"color: windowtext;\">10.1016\/j.tetlet.2017.03.005<\/span><\/span><\/a><\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u00a0<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u2013Synthesis\u00a0\u00a0\u00a0 and\u00a0\u00a0\u00a0 carbonic\u00a0anhydrase\u00a0\u00a0\u00a0 inhibitory\u00a0\u00a0\u00a0 effects\u00a0 \u00a0of\u00a0\u00a0\u00a0 new\u00a0\u00a0\u00a0 <i>N<\/i>-glycosylsulfonamides incorporaiting the phenol moiety. <\/span><span lang=\"ES\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: ES;\">L. E. Riafrecha, S. Bua, C. T. Supuran and P. A. Colinas. <\/span><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">Bioorganic and Medicinal Chemistry Letters <b>2016<\/b>, 26, 3892\u20133895.<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">DOI: 10.1016\/j.bmcl.2016.07.015<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u00a0<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u2013Anti\u2013tubercular and antioxidant activities of <i>C<\/i>-glycosyl carbonic anhydrase inhibitors: Towards the development<br \/>of novel chemotherapeutic agents against Mycobacterium tuberculosis. <\/span><span lang=\"ES\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: ES;\">M. J. Zaro, A. Bortolloti, L. E. Riafrecha, A. Concell\u00f3n, H. R. Morbidoni, P. A. Colinas. <\/span><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">Journal of Enzyme Inhibition and Medicinal Chemistry <b>2016<\/b>, 31, 1726\u20131730.<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">DOI:10.3109\/14756366.2016.1172577<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u00a0<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u2013Inhibition\u00a0 of\u00a0 <\/span><span lang=\"ES\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: ES;\">\u03b2<\/span><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u2013carbonic\u00a0 anhydrases\u00a0 from\u00a0 Brucella\u00a0 suis\u00a0 with\u00a0 <i>C<\/i>\u2013cinnamoyl glycosides incorporating the phenol moiety. L. E. Riafrecha, D. Vullo, S. Ouahrani-Bettache, S. K\u00f6hler, P. Dumy, J.\u2013Y. Winum, C. T. Supuran and P. A. Colinas. Journal of Enzyme Inhibition and Medicinal Chemistry <b>2015<\/b>, 30, 1017\u20131020.<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u00a0DOI:\u00a0<\/span><span lang=\"EN-US\" style=\"font-size: 12.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\"><a href=\"https:\/\/doi.org\/10.3109\/14756366.2014.986120\" target=\"_blank\" rel=\"noopener\"><span style=\"color: windowtext;\">10.3109\/14756366.2014.986120<\/span><\/a><\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u2013<i>C<\/i>-glycosides incorporating the 6\u2013methoxy\u20132\u2013naphthyl moiety are selective inhibitors of fungal and bacterial<br \/>carbonic anhydrases. <\/span><span lang=\"ES\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: ES;\">L. E. Riafrecha, D. Vullo, C. T. Supuran and P. A. Colinas. <\/span><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">Journal of Enzyme Inhibition and Medicinal Chemistry <b>2015<\/b>, 30, 857\u2013861.<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">DOI:10.3109\/14756366.2014.967233<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u00a0<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u2013Attachment of carbohydrates to methoxyaryl moieties leads to highly selective inhibitors of the cancer associated carbonic anhydrase isoforms IX and XII. L. E. Riafrecha, O. M. Rodr\u00edguez, D. Vullo, C. T. Supuran and P. A. Colinas. Bioorganic and Medicinal Chemistry <b>2014<\/b>, 22, 5308\u20135314.<\/span><\/p><p><span style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif;\">DOI:\u00a0<\/span><span lang=\"EN-US\" style=\"font-size: 12.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\"><a href=\"https:\/\/doi.org\/10.1016\/j.bmc.2014.07.052\" target=\"_blank\" rel=\"noopener\"><span style=\"color: windowtext;\">10.1016\/j.bmc.2014.07.052<\/span><\/a><\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u2013Novel sulfonamide compounds for inhibition of metastatic tumor growth (WO2012021963). P. A. Colinas. Expert Opinion on Therapeutic Patents <b>2013<\/b>, 23, 761\u2013763.<\/span><\/p><p><span style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif;\">DOI:\u00a0<\/span><span lang=\"EN-US\" style=\"font-size: 12.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\"><a href=\"https:\/\/doi.org\/10.1517\/13543776.2013.789023\" target=\"_blank\" rel=\"noopener\"><span style=\"color: windowtext;\">10.1517\/13543776.2013.789023<\/span><\/a><\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u2013Inhibition of the <\/span><span lang=\"ES\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: ES;\">\u03b2<\/span><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u2013carbonic anhydrases from Mycobacterium tuberculosis with <i>C<\/i>-cinnamoyl glycosides:\u00a0 identification of the first inhibitor with antimycobacterial activity. <\/span><span lang=\"ES\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: ES;\">M. V. Buccheri, L. E. Riafrecha, M. O. Rodr\u00edguez, D. Vullo, H. R. Morbidoni, C. T. Supuran, P. A. Colinas. <\/span><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">Bioorganic and Medicinal Chemistry Letters <b>2013<\/b>, 23, 740\u2013743.<\/span><\/p><p><span style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif;\">DOI:\u00a0<\/span><span lang=\"EN-US\" style=\"font-size: 12.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\"><a href=\"https:\/\/doi.org\/10.1016\/j.bmcl.2012.11.085\" target=\"_blank\" rel=\"noopener\"><span style=\"color: windowtext;\">10.1016\/j.bmcl.2012.11.085<\/span><\/a><\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u00a0<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u2013Synthesis of <i>C<\/i>\u2013cinnamoyl glycosides and their inhibitory activity against mammalian carbonic anhydrases. <\/span><span lang=\"ES\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: ES;\">L. E. Riafrecha, O. M. Rodr\u00edguez, D. Vullo, C. T. Supuran and P. A. Colinas. <\/span><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">Bioorganic and Medicinal Chemistry <b>2013<\/b>, 21, 1489\u20131494<\/span><\/p><p><span style=\"font-size: 12.0pt; line-height: 107%; font-family: 'Arial',sans-serif;\">DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1016\/j.bmc.2012.09.002\" target=\"_blank\" rel=\"noopener\"><span style=\"color: windowtext;\">10.1016\/j.bmc.2012.09.002<\/span><\/a><\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u2013Glycosidic CA IX inhibitors: a sweet approach against cancer. J. Y. Winum, P.A. Colinas and C. T. Supuran. Bioorganic and Medicinal Chemistry <b>2013<\/b>, 21, 1419\u20131426.<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u00a0DOI: 10.1016\/j.bmc.2012.10.043<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u00a0<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u2013Conformational behavior of peracetylated <\/span><span lang=\"ES\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: ES;\">\u03b2<\/span><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u2013D\u2013mannopyranosyl methanesulfonamide: implications for the mechanism of sulfonamidoglycosylation of carbohydrate derivatives. <\/span><span lang=\"ES\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: ES;\">M. J. Lavecchia, O. M. Rodr\u00edguez, G. A. Echeverr\u00eda, R. Pis Diez and P. A. Colinas. <\/span><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">Carbohydrate Research <b>2012<\/b>, 361, 182\u2013188.<\/span><\/p><p><span style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif;\">DOI:<\/span><span lang=\"EN-US\" style=\"font-size: 12.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u00a0<a href=\"https:\/\/doi.org\/10.1016\/j.carres.2012.08.016\" target=\"_blank\" rel=\"noopener\"><span style=\"color: windowtext;\">10.1016\/j.carres.2012.08.016<\/span><\/a><\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u2013Crystal\u00a0\u00a0 structure,\u00a0\u00a0 Spectroscopy\u00a0\u00a0 and\u00a0 theoretical\u00a0\u00a0 studies\u00a0\u00a0 of\u00a0 p\u2013cyano\u2013 benzenosulfonamide and a Cu (II) complex. <\/span><span lang=\"ES\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: ES;\">G. Cam\u00ed, E. Chac\u00f3n Villalba, P.Colinas, G. A. Echeverr\u00eda, G. Estiu and D.B. Soria. <\/span><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">Journal of Molecular Structure <b>2012<\/b>, 1024, 110\u2013116.<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">DOI:<\/span><span lang=\"EN-US\" style=\"font-size: 12.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\"><a href=\"http:\/\/dx.doi.org\/10.1016\/j.molstruc.2012.05.006\" target=\"_blank\" rel=\"noopener\"><span lang=\"ES-AR\" style=\"color: windowtext;\">10.1016\/j.molstruc.2012.05.006<\/span><\/a><\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u2013Novel Glycomimetics: Anomeric and <i>N<\/i>-Glycosyl Sulfonamides. P. A. Colinas. Current Organic Chemistry <b>2012<\/b>, 16 (14), 1670\u20131679.<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">DOI:10.2174\/138527212800840892<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u00a0<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u2013 <i>N<\/i>\u2013<\/span><span lang=\"ES\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: ES;\">\u03b2<\/span><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">-glycosyl sulfamides are selective inhibitors of the cancer associated carbonic anhydrase isoforms IX and XII. O. M. Rodr\u00edguez, A. Maresca, C. A. T\u00e9mpera, R. D. Bravo, P. A. Colinas and C. T. Supuran. Bioorganic and Medicinal Chemistry Letters <b>2011<\/b>, 21, 4447\u20134450.<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">DOI: 10.1016\/j.bmcl.2011.06.031<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u00a0<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u2013Synthesis, Thermogravimetric, Spectroscopic and Theoretical Characterization of copper (II) complex with 4\u2013chloro\u20132\u2013nitrobenzenosulphonamide. <\/span><span lang=\"ES\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: ES;\">G. Cam\u00ed, E. Chac\u00f3n Villalba, Y. Di Santi, P.Colinas, G. Estiu and D.B. Soria. <\/span><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">Journal of Molecular Structure <b>2011<\/b>, 995, 72\u201377.<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">DOI: 10.1016\/j.molstruc.2011.03.059<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u00a0<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u2013A\u00a0 combined\u00a0 theoretical\u00a0 and\u00a0 spectroscopic\u00a0 study\u00a0 of\u00a0 4,6\u2013di\u2013<i>O<\/i>\u2013acetyl\u20132,3\u2013dideoxy\u2013D- erythro\u2013hex\u20132\u2013enopyranosyl sulfamide: a novel glycosyl carbonic anhydrase IX inhibitor. M. J Lavecchia, R. Pis Diez and P. A. Colinas Carbohydrate Research <b>2011<\/b>, 346, 442\u2013448.<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">DOI:<\/span><span lang=\"EN-US\" style=\"font-size: 12.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\"><a href=\"http:\/\/dx.doi.org\/10.1016\/j.carres.2010.07.019\" target=\"_blank\" rel=\"noopener\"><span style=\"color: windowtext;\">10.1016\/j.carres.2010.07.019<\/span><\/a><\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u2013In vitro antitumor activity of N-glycosyl sulfonamides. R. Crespo, M. G. de Bravo, P. A. Colinas and R. D. Bravo Bioorganic and Medicinal Chemistry Letters\u00a0<b>2010<\/b>, 20, 6469\u20136471.<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">DOI:10.1016\/j.bmcl.2010.09.052<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u00a0<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">\u2013Efficient synthesis of 2, 3\u2013unsaturated sulfonamidoglycosides by Amberlyst 15. C. A. T\u00e9mpera, P. A. Colinas and R. D. BravoTetrahedron Letters <b>2010<\/b>, 51, 5372\u20135374.<\/span><\/p><p><span lang=\"EN-US\" style=\"font-size: 12.0pt; mso-bidi-font-size: 11.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">DOI:<\/span><span lang=\"EN-US\" style=\"font-size: 12.0pt; line-height: 107%; font-family: 'Arial',sans-serif; mso-ansi-language: EN-US;\">10.1016\/j.tetlet.2010.07.076<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Publicaciones &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;\u00faltimos 15 a\u00f1os&#8230; -An Efficient Synthetic Methodology for the Preparation of Glycosyl \u03b2-Diketones. I. A. Barri, M. S. Le Pors and P. A. Colinas. European Journal of Organic Chemistry 2025. DOI: 10.1002\/ejoc.202401366 -Glucoimines incorporating classical and non-classical carbonic anhydrase pharmacophores: design, synthesis, conformational analysis, biological evaluation, and docking simulations. I. I. V\u00e1squez, L. E. Riafrecha, L. Mart\u00ednez Heredia, G. A. Echeverr\u00eda, O. E. Piro, M.J. Lavecchia, C.T. Supuran and P. A. Colinas. Journal of molecular structure 2024, 1321,139798. DOI: 10.1016\/j.molstruc.2024.139778 \u2013Spontaneous resolution of diastereomeric glycosyl isoxazolines: a combined theoretical and experimental study in solution and in the crystalline form. I. A. Barri, L. E. Riafrecha, G. A. Echeverr\u00eda,\u00a0 O. E. Piro\u00a0 and P. A. Colinas. Journal of molecular structure 2024. 1310,138252 DOI: 10.1016\/j.molstruc.2024.138252 \u2013Glycosyl Isoxazoles for Targeting of Tumor Microenvironment and Cancer Cells: Highly Selective Inhibitors of Carbonic Anhydrases IX and XII Showing Cytotoxic Activity. M.S. Le Pors, L. Santa Mar\u00eda de la Parra, L.E. Riafrecha, D. Vullo, I.E. Leon, C.T. Supuran and P.A. Colinas. ChemistrySelect 2023, 8(11). 10.1002\/slct.202300039. DOI:10.1002\/slct.202300039 \u2013Green Biphasic Synthesis, X\u2013Ray Diffraction Structure and Conformational Analysis of O\u2013GlycosylmethylIsoxazoles: Potential Substrates of GLUT-1 Glucose Transporter. M.S. Le Pors, I.A. Barri, L. E.\u00a0 Riafrecha, G. A. Echeverr\u00eda, O. Piro and P. A. Colinas.\u00a0ChemistrySelect\u00a02022, 26, 2601\u20132608. DOI: 10.1002\/slct.202104379 \u2013Vanillin enones as selective inhibitors of the cancer associated carbonic anhydrase isoforms IX and XII. The out of the active site pocket for the design of selective inhibitors? .L. E.\u00a0 Riafrecha, M.S. LePors, M.J. Lavecchia, S. Bua, C. T: Supuran and P. A. Colinas. Journal of enzyme inhibition and medicinal chemistry 2021, 36 (1), 2118\u20132127. DOI:\u00a010.1080\/14756366.2021.1982933 \u2013C\u2013cinnamoyl\u00a0\u00a0 glycosides:\u00a0 an\u00a0\u00a0 emerging\u00a0\u00a0 \u201ctail\u201d\u00a0 \u00a0for the development of selective carbonic anhydrase inhibitors. H. Llant\u00e9n, L. E.\u00a0 Riafrecha and P. A. Colinas. Current Medicinal Chemistry 2019, 26, 2601\u20132608. DOI:\u00a010.2174\/0929867325666180713122907 \u2013Improving the carbonic anhydrase inhibition profile of the sulfamoylphenyl pharmacophore by attachment of carbohydrate moieties. L. E. Riafrecha, S. Bua, C. T. Supuran and P. A. Colinas. Bioorganic Chemistry 2018, 76, 61\u201366. DOI:10.1016\/j.bioorg.2017.10.020 \u00a0 \u2013Synthesis of C-glycosylmethyl isoxazoles via aerobic oxidation of ketoximes catalyzed by TEMPO. H. Llant\u00e9n, S.Barata\u2013Vallejo, A. Postigo and P. A. Colinas. Tetrahedron Letters 2017, 58, 1507\u20131511. DOI: 10.1016\/j.tetlet.2017.03.005 \u00a0 \u2013Synthesis\u00a0\u00a0\u00a0 and\u00a0\u00a0\u00a0 carbonic\u00a0anhydrase\u00a0\u00a0\u00a0 inhibitory\u00a0\u00a0\u00a0 effects\u00a0 \u00a0of\u00a0\u00a0\u00a0 new\u00a0\u00a0\u00a0 N-glycosylsulfonamides incorporaiting the phenol moiety. L. E. Riafrecha, S. Bua, C. T. Supuran and P. A. Colinas. Bioorganic and Medicinal Chemistry Letters 2016, 26, 3892\u20133895. DOI: 10.1016\/j.bmcl.2016.07.015 \u00a0 \u2013Anti\u2013tubercular and antioxidant activities of C-glycosyl carbonic anhydrase inhibitors: Towards the developmentof novel chemotherapeutic agents against Mycobacterium tuberculosis. M. J. Zaro, A. Bortolloti, L. E. Riafrecha, A. Concell\u00f3n, H. R. Morbidoni, P. A. Colinas. Journal of Enzyme Inhibition and Medicinal Chemistry 2016, 31, 1726\u20131730. DOI:10.3109\/14756366.2016.1172577 \u00a0 \u2013Inhibition\u00a0 of\u00a0 \u03b2\u2013carbonic\u00a0 anhydrases\u00a0 from\u00a0 Brucella\u00a0 suis\u00a0 with\u00a0 C\u2013cinnamoyl glycosides incorporating the phenol moiety. L. E. Riafrecha, D. Vullo, S. Ouahrani-Bettache, S. K\u00f6hler, P. Dumy, J.\u2013Y. Winum, C. T. Supuran and P. A. Colinas. Journal of Enzyme Inhibition and Medicinal Chemistry 2015, 30, 1017\u20131020. \u00a0DOI:\u00a010.3109\/14756366.2014.986120 \u2013C-glycosides incorporating the 6\u2013methoxy\u20132\u2013naphthyl moiety are selective inhibitors of fungal and bacterialcarbonic anhydrases. L. E. Riafrecha, D. Vullo, C. T. Supuran and P. A. Colinas. Journal of Enzyme Inhibition and Medicinal Chemistry 2015, 30, 857\u2013861. DOI:10.3109\/14756366.2014.967233 \u00a0 \u2013Attachment of carbohydrates to methoxyaryl moieties leads to highly selective inhibitors of the cancer associated carbonic anhydrase isoforms IX and XII. L. E. Riafrecha, O. M. Rodr\u00edguez, D. Vullo, C. T. Supuran and P. A. Colinas. Bioorganic and Medicinal Chemistry 2014, 22, 5308\u20135314. DOI:\u00a010.1016\/j.bmc.2014.07.052 \u2013Novel sulfonamide compounds for inhibition of metastatic tumor growth (WO2012021963). P. A. Colinas. Expert Opinion on Therapeutic Patents 2013, 23, 761\u2013763. DOI:\u00a010.1517\/13543776.2013.789023 \u2013Inhibition of the \u03b2\u2013carbonic anhydrases from Mycobacterium tuberculosis with C-cinnamoyl glycosides:\u00a0 identification of the first inhibitor with antimycobacterial activity. M. V. Buccheri, L. E. Riafrecha, M. O. Rodr\u00edguez, D. Vullo, H. R. Morbidoni, C. T. Supuran, P. A. Colinas. Bioorganic and Medicinal Chemistry Letters 2013, 23, 740\u2013743. DOI:\u00a010.1016\/j.bmcl.2012.11.085 \u00a0 \u2013Synthesis of C\u2013cinnamoyl glycosides and their inhibitory activity against mammalian carbonic anhydrases. L. E. Riafrecha, O. M. Rodr\u00edguez, D. Vullo, C. T. Supuran and P. A. Colinas. Bioorganic and Medicinal Chemistry 2013, 21, 1489\u20131494 DOI:\u00a010.1016\/j.bmc.2012.09.002 \u2013Glycosidic CA IX inhibitors: a sweet approach against cancer. J. Y. Winum, P.A. Colinas and C. T. Supuran. Bioorganic and Medicinal Chemistry 2013, 21, 1419\u20131426. \u00a0DOI: 10.1016\/j.bmc.2012.10.043 \u00a0 \u2013Conformational behavior of peracetylated \u03b2\u2013D\u2013mannopyranosyl methanesulfonamide: implications for the mechanism of sulfonamidoglycosylation of carbohydrate derivatives. M. J. Lavecchia, O. M. Rodr\u00edguez, G. A. Echeverr\u00eda, R. Pis Diez and P. A. Colinas. Carbohydrate Research 2012, 361, 182\u2013188. DOI:\u00a010.1016\/j.carres.2012.08.016 \u2013Crystal\u00a0\u00a0 structure,\u00a0\u00a0 Spectroscopy\u00a0\u00a0 and\u00a0 theoretical\u00a0\u00a0 studies\u00a0\u00a0 of\u00a0 p\u2013cyano\u2013 benzenosulfonamide and a Cu (II) complex. G. Cam\u00ed, E. Chac\u00f3n Villalba, P.Colinas, G. A. Echeverr\u00eda, G. Estiu and D.B. Soria. Journal of Molecular Structure 2012, 1024, 110\u2013116. DOI:10.1016\/j.molstruc.2012.05.006 \u2013Novel Glycomimetics: Anomeric and N-Glycosyl Sulfonamides. P. A. Colinas. Current Organic Chemistry 2012, 16 (14), 1670\u20131679. DOI:10.2174\/138527212800840892 \u00a0 \u2013 N\u2013\u03b2-glycosyl sulfamides are selective inhibitors of the cancer associated carbonic anhydrase isoforms IX and XII. O. M. Rodr\u00edguez, A. Maresca, C. A. T\u00e9mpera, R. D. Bravo, P. A. Colinas and C. T. Supuran. Bioorganic and Medicinal Chemistry Letters 2011, 21, 4447\u20134450. DOI: 10.1016\/j.bmcl.2011.06.031 \u00a0 \u2013Synthesis, Thermogravimetric, Spectroscopic and Theoretical Characterization of copper (II) complex with 4\u2013chloro\u20132\u2013nitrobenzenosulphonamide. G. Cam\u00ed, E. Chac\u00f3n Villalba, Y. Di Santi, P.Colinas, G. Estiu and D.B. Soria. Journal of Molecular Structure 2011, 995, 72\u201377. DOI: 10.1016\/j.molstruc.2011.03.059 \u00a0 \u2013A\u00a0 combined\u00a0 theoretical\u00a0 and\u00a0 spectroscopic\u00a0 study\u00a0 of\u00a0 4,6\u2013di\u2013O\u2013acetyl\u20132,3\u2013dideoxy\u2013D- erythro\u2013hex\u20132\u2013enopyranosyl sulfamide: a novel glycosyl carbonic anhydrase IX inhibitor. M. J Lavecchia, R. Pis Diez and P. A. Colinas Carbohydrate Research 2011, 346, 442\u2013448. DOI:10.1016\/j.carres.2010.07.019 \u2013In vitro antitumor activity of N-glycosyl sulfonamides. R. Crespo, M. G. de Bravo, P. A. Colinas and R. D. Bravo Bioorganic and Medicinal Chemistry Letters\u00a02010, 20, 6469\u20136471. DOI:10.1016\/j.bmcl.2010.09.052 \u00a0 \u2013Efficient synthesis of 2, 3\u2013unsaturated sulfonamidoglycosides by Amberlyst 15. C. A. T\u00e9mpera, P. A. Colinas and R. D. BravoTetrahedron Letters 2010, 51, 5372\u20135374. 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